Molecularly imprinted solid-phase extraction of cocaine metabolites from aqueous samples [An article from: Analytica Chimica Acta] - Cocaine - Pass Drug Test

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Molecularly imprinted solid-phase extraction of cocaine metabolites from aqueous samples [An article from: Analytica Chimica Acta]
	Authors: A. Zurutuza, S. Bayoudh, P.a.g. Cormack, Dambies Publisher: Elsevier Category: Book Buy New: $10.95 Format: Html Language: English (Published) Media: Digital Pages: 5 ASIN: B000RR3F76 Publication Date: June 22, 2005 Availability: Available for download now

Editorial Reviews: Product Description This digital document is a journal article from Analytica Chimica Acta, published by Elsevier in 2005. The article is delivered in HTML format and is available in your Amazon.com Media Library immediately after purchase. You can view it with any web browser. Description: Cocaine is a well-known drug of abuse which, when ingested nasally or by smoking, undergoes a number of biotransformation and degradation reactions. In the present work, a synthetic analogue of the cocaine metabolite benzoylecgonine was prepared and used as a template molecule in the preparation of a series of molecularly imprinted polymers (MIPs). Molecularly imprinted solid-phase extraction (MISPE) conditions were established under which benzoylecgonine in aqueous samples could be selectively extracted and quantified at clinically relevant concentrations (@mg/ml). Under optimised MISPE conditions, recoveries of analyte were high (>70%) and excellent discrimination between imprinted and non-imprinted materials observed.